Glysolin 30/70 Mechanism of Action

Pharmacology: Phamacodynamics: Mechanism of Action: Like all other insulins, the glucose lowering effect of Biphasic Isophane Insulin (Glysolin 30/70) is due to the facilitated uptake of glucose in body tissues.
This uptake occurs following the binding of insulin to its receptors present in the muscle and adipose tissue.
The blood glucose lowering effect of insulin also occurs due to the simultaneous inhibition of glucose output from the liver.
Pharmacokinetics: Insulin has a half-life of a few minutes in the blood stream. Consequently, the time course of action of any insulin may vary considerably in different individuals or at different times in the same individual. As with insulin preparations, the intensity and duration of action of Biphasic Isophane Insulin (Glysolin 30/70) is dependent on the dose, site of injection, blood supply, temperature, and physical activity.
An average action profile after subcutaneous injection indicates: Onset within 0.5 hours; Peak levels attained between 2-12 hours; Duration of action approximately 18-24 hours.